Addiction

Study Examines Environmental Impact on Addiction Relapse

Addiction can control a life, making it difficult to kick a habit completely. Even those who have been able to remain abstinent for long periods of time are still at risk of being vulnerable to their own memories of prior drug or substance abuse.

A recent Science Daily release focused on a recent study that found exposure to the same environment in which the addict commonly used a substance can increase the craving for that substance dramatically, often leading to relapse. This study examined the novel compound that may ease the power of such memories.

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Using Nicotine Patch before Quitting Smoking Doubles Success Rate

Duke University Medical Center researchers recently found that using a nicotine patch before quitting smoking can double success rates. They say their findings should be printed on nicotine patch labeling.

Currently, the nicotine patch is only recommended for use after the quit date, explained Jed Rose, director of the Duke Center for Nicotine and Smoking Research and lead author of the study. This resulted from concerns that using a patch while smoking could lead to nicotine overdose. However, the new study found that concurrent use of a nicotine patch and cigarettes appears to be safe.

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Drug Treatment Demand on the Rise

The fact that drug treatments are available is a positive move in the direction of progress toward a healthier community. When the demand increases among adults for these treatments, one has to ask the question: does this mean that drug use is up or those seeking to stop is increasing?

A recent news piece out of Frederick County reported that the demand for drug addiction services among adults increased by more than 25 percent in the past year. Katherine A. Shriver, Frederick County Health Department Substance Abuse Division director noted that the reason for the increase is likely tied to the economy.

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Graphic Ads Help Prevent Meth Use

By Colin Gilbert

Methamphetamine abuse has become a serious problem among teenagers and young adults in Idaho. In 2007, the state ranked fourth in the country for meth use among individuals aged 12-25, and more than half of Idaho’s prison inmates acknowledged the drug as being directly involved with their initial imprisonment. It’s an alarming trend, but a recent advertising campaign from the Idaho Meth Project is working to stop users before they start.

In 2005, the Meth Project was formed to address what is still considered the number-one problem in Idaho—methamphetamine abuse. The powerful, highly addictive drug, which is often made in home “meth labs,” has become a widespread menace among the state’s youth, and the private, non-profit organization is founded on a passion for prevention. Their motto is simple—“Not even once.”

Beginning in January of 2008, the group released a series of graphic television commercials, billboards, radio spots, and print ads that were specifically designed to deter potential users through shocking factual evidence. In January of 2009, another wave of advertisements was released, and the Meth Project estimated that they would reach 70-90 percent of Idaho’s teens 3-5 times a week throughout the year.

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More Women Using Cocaine in the UK

The Telegraph UK reported that one in 15 women ages 10-25 in England admitted they have tried cocaine, raising concerns that young women will soon overtake men for cocaine use. Unfortunately, cocaine is being considered more glamorous and socially acceptable, with high-profile celebrities like Kate Moss and Amy Winehouse being associated with the drug.

The increase in female cocaine users parallels the recent increase in female binge drinkers. The co-author of the study, Jim McVeigh, says that the findings shouldn’t be surprising because “we have seen the same thing happening with alcohol, which is intrinsically linked with cocaine.”

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Gender Differences Play a Role in Addiction

Drug abuse and addiction affect women and men differently, according to new studies presented at the annual meeting of the American Psychiatric Association. Some of the speakers asserted that this knowledge of gender-based differences should be used in pharmacological and behavioral treatments for addiction.

Women begin using drugs at lower doses then men, their drug use escalates more rapidly into addiction, and they face a greater risk of relapse after abstinence, according to Jill Becker, PhD, professor of psychology at the University of Michigan, Ann Arbor. In addition to the direct evidence from humans, laboratory animals show the same kind of gender differences in addiction. Studies by Christine E. Grella, PhD, research psychologist at the University of California, Los Angeles also show that women tend to enter treatment sooner after becoming dependent on substances than men, but they usually have more psychological distress, particularly with mood and anxiety disorders.

Addiction is widely considered a disorder of the memory processes, and over the past several years, studies have shown strong hemispheric gender differences in how the brain responds to memory processing after seeing emotionally arousing material. For example, men show stronger responses in the right amygdala, and women have stronger responses in the left amygdala. This research may help to explain previous evidence for effects of the menstrual cycle on craving in addition to gender differences in the effectiveness of addiction treatments such as the nicotine patch.

Karen Faith Berman, MD, and colleagues at the National Institute of Mental Health in Bethesda, Maryland, had found that fluctuations in steroid hormone levels during the menstruation cycle affect neurological responses to rewards. When anticipating an uncertain reward, men showed more activity in the ventral putamen than women; when receiving a reward, women showed more activity in the anterior medial prefrontal cortex than men.

Becker’s team has also found significant gender differences in the concentration and location of receptors for the neurotransmitter dopamine, which controls anticipation and reward. The female hormone estradiol enhances dopamine release among women, for example. “Since the effect of estradiol is seen only in females,” Becker said, “this mechanism may offer unique pharmacological opportunities for the treatment of drug abuse in women.”

Cocaine also seems to dampen normal gender differences in response to stress, craving, and relaxation, said Marc N. Potenza MD, PhD, associate professor in the department of psychiatry at Yale University.

Larry Cahill, PhD, associate professor of neurobiology and behavior at the School of Biological Sciences, University of California, Irvine, said, “It is dangerous at best, and completely wrong at worst, to assume that any neurological disorder has the same underlying causes in men and women, and thus to assume that treatments for the disorder will be essentially the same…Yet that is precisely the assumption that continues to pervade much of both the clinically applied and basic science worlds.”

Source: Psychiatric Times, May 2009

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Cocaine Use Among U.S. Workers Down, Amphetamines Up

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Statistics from Quest Diagnostics, the world’s largest provider of diagnostic tests, show that fewer U.S. workers used cocaine or methamphetamines in 2008 than in 2007, but that more took amphetamines. Based on 5.7 million urine tests analyzed by Quest, the findings said cocaine use fell to 0.47% from 0.58%, but that amphetamine use rose from 5.3% to 12.5%.

“While many substances are showing declines in use, a significant trend upward that will be important to watch is the rise in amphetamine positives,” said Robert Willette, a former research chief at the National Institute on Drug Abuse in Bethesda, Maryland.

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All in Our Heads: How the Brain Creates Addiction

By Meghan O’Dell

brain1It wasn’t very long ago that most people considered addiction to be a moral failing rather than a treatable disease-it was largely thought that people who succumbed to drugs and alcohol were simply making poor decisions. Even when the American Medical Association announced in 1950 that alcoholism is a disease, people continued to hold onto the belief that addiction was voluntary. But now scientists have been able to pinpoint exactly what happens in the brain of an addict, proving that addiction is a disease and that the brain can make it very difficult for people to resist the effects of drugs and alcohol.

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Research Suggests Alcohol More Damaging than Marijuana

In the countless national campaigns that stress to students the importance of staying away from drugs and alcohol, the younger generation is led to believe that both categories are inherently bad and have the same adverse effects. Instead, recent Clinical EEG and Neuroscience news suggests that alcohol is far more damaging than marijuana when measuring the impact on adolescents.

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Salvia: More Harmful than Marijuana and Growing in Use

While marijuana has long been used by people to achieve a desired euphoria, a new and more potent weed has emerged on the market and is finding a strong following. The weed is salvia and as reported by the Telegraph, it is far more harmful than marijuana has ever been.

The average salvia user is in their teens or twenties and most have been able to buy salvia on the Internet. Those who use salvia are often reduced to mumbling wrecks, giggling and screaming, gasping and muttering, waving their hands around as they sink to the floor. Much of this type of performance has been captured numerous times and broadcasted on YouTube for the world to see.

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