Most people have experienced a time in life when situations or events may have triggered periods of melancholy or an overall sense of feeling down. It’s normal, at one time or another, to feel depression following something sad or distressing that has happened. Usually, these feelings will naturally fade away over a few days or weeks. But when feelings of sadness are accompanied by a loss of interest in activities that were once enjoyable, and last for two or more months, major depression is likely the culprit. Typically, treatment for depression includes therapy, medication or a combination of the two. Depending on the situation, a doctor may prescribe an antidepressant such as trazodone for depression. What Are Antidepressants? Antidepressants are medications typically used to treat depression, but can also be used to treat anxiety, insomnia and some forms of pain. Studies have shown that when a person suffers from depression, circuits in the brain and central nervous system do not function properly. The circuits do not effectively transfer the main neurotransmitters (chemicals), norepinephrine, serotonin and dopamine within the brain. Antidepressants work by helping to repair the brain’s circuitry and neurotransmitter function. How a person responds to antidepressant use varies. Statistics...